Principal Investigator/Research Scientist

Research Scientist – iPSC and Organoid Modeling

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Location: New York City (in-person, full-time)

Salary range: $70,000 – $100,000

Organization: Tisch Multiple Sclerosis Research Center of New York (Tisch MSRCNY)

About us

At Tisch MSRCNY, under the leadership of Dr. Saud A. Sadiq, MD, FAAN, we are dedicated to unraveling the causes of and finding a cure for multiple sclerosis. Our interdisciplinary approach fosters collaboration between scientists and clinicians, accelerating translational research and the development of innovative therapeutic strategies for MS.

Position Overview

We are seeking a motivated Research Scientist to participate in innovative multiple sclerosis research focused on induced pluripotent stem cell (iPSC)-derived 2D and 3D neural culture systems, including cerebral organoid models. The successful candidate will contribute to the development and characterization of stem cell-based models to investigate glial and neuronal mechanisms associated with neuroinflammation, neurodegeneration, and repair in multiple sclerosis.

This position is ideal for a junior scientist seeking to expand their expertise in stem cell biology, organoid modeling, and translational neuroscience within a highly collaborative research environment.

What We Offer:

Fully Funded Position: This role is secured for three years, with the potential for extension.

Collaborative Environment: Work alongside leading experts in multiple sclerosis research and contribute to interdisciplinary research projects.

Cutting-Edge Research: Engage in groundbreaking studies involving iPSC-derived neural systems, cerebral organoids, and neuroimmune disease modeling.

Career Development: Opportunities for scientific mentorship, publication, and professional growth within a dynamic academic research setting.

Compensation and Benefits: Competitive salary and comprehensive benefits package.

Qualifications:

PhD or MD/PhD in neuroscience, stem cell biology, immunology, cell biology, or a related biological science.

Postdoctoral or hands-on research experience in areas relevant to neurobiology, stem cells, or disease modeling preferred.

Experience with mammalian cell culture required.

Experience with human iPSC culture, neural differentiation, or cerebral organoid systems preferred.

Experience with molecular and cellular biology techniques such as immunocytochemistry, fluorescence/confocal microscopy, qPCR, flow cytometry, or RNA analysis.

Strong organizational, communication, and problem-solving skills.

Ability to work independently while contributing effectively within a collaborative research environment.

Strong scientific publication record appropriate to career stage.

Experience with neuroinflammatory or neurodegenerative disease models is a plus.

Familiarity with high-content imaging, single-cell analysis, or electrophysiology is a plus.

Applicants must be U.S. citizens or permanent residents.

How to Apply

To apply, please submit a cover letter, CV, and contact information for three references to:

Email: [email protected]

Subject line: “Research Scientist Application”

About Tisch Multiple Sclerosis Research Center Of New York Inc

Tisch MS Research Center of New York is an independent nonprofit 501(c)(3) organization committed to finding the cause of, and a cure for, multiple sclerosis. Led by neurologist Dr. Saud Sadiq, MD, FAAN, the Tisch MSRCNY team conducts multidisciplinary, industry-leading research that includes all aspects of the disease including progression mechanisms, translational programs that will lead to new therapies, and the regeneration and repair process. With industry-renowned principal researchers and a thriving Assistantship Program for young scientists, Tisch MSRCNY accelerates the pace at which research moves from lab bench to bedside.